Association between Raised Serum C-Reactive Protein and Arteriovenous Fistula Failure

  • Rashid Usman Department of Vascular Surgery Combined Military Hospital, Lahore Cantt
  • Muhammad Jamil Department of Vascular Surgery Combined Military Hospital Peshawar Cantt
  • Hanif Abbassi Department of Surgery Combined Military Hospital Peshawar Cantt
Keywords: C-reactive protein, Arteriovenous fistula

Abstract

Objectives: To study the association between serum Creactive protein (CRP) and arteriovenous fistula (AVF) failure rate.
Patients and Methods: This case control study Department of Vascular Surgery Combined Military Hospital Lahore and Peshawar between January 2015 and March 2016. Total 126 consecutive patients who had serum CRP checked preoperatively and underwent AVF procedure were included. Patients were divided into Case (with raised CRP) and Control (Normal CRP) groups. Data regarding serum CRP level were recorded and analysed to evaluate the impact of preoperative CRP levels on AVF failure rates.
Results: The AVF failure rate was significantly high (53.2%) in case group as compared to control group (14.5%). Age, gender, diabetes and hypertension did not show statistically significant difference between the two groups.
Conclusion:
Raised level of CRP is related to significantly higher AVF maturation failure rate. Therefore, it is recommended to check CRP levels preoperatively to identify those patients who can be at higher risk of fistula failure. 

Published
2017-01-08
Section
Original Articles