Correlation of Duration of Hepatitis C Infection with Triglycerides and Total Cholesterol
Abstract
Objective: To study the correlation of duration of chronic HCV infection with total cholesterol and triglycerides.
Patients & Methods: In this cross-sectional observational study we recruited 37 HCV infected patients who were diagnosed at least 6 months ago. Seven patients were excluded due to hyperglycemia. Patients suffering from metabolic disorders affecting total cholesterol and triglycerides were also excluded. Serum triglycerides, total cholesterol, and plasma glucose were measured by enzymatic method. Data was entered on SPSS version 16. Mean, standard deviation was calculated for numerical data. Pearson correlation was used to find association of duration of HCV with Total Cholesterol and Triglycerides.
Results: Mean age of 30 subjects was 39.9±9.5 years, duration of HCV infection was 4.1±3.4 years and mean fasting plasma glucose was 81.7±6.4mg/dl. Total cholesterol and triglycerides were 107±30mg/dl and 72.3±23.5mg/dl respectively. Triglycerides showed a significant correlation with duration of HCV infection (p=0.024) and total cholesterol (p=0.001). Conclusion: There is a significant correlation of triglycerides with duration of HCV infection (p=0.024) and total cholesterol (p=0.001).
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