Effect of Different Sizes of Intraocular Lens on Early Changes of Posterior Capsular Opacification

Abstract

Objectives: To evaluate the effect of different sizes of Intra Ocular lens (IOL) on frequency of development of early changes of posterior capsular opacification (PCO)
Patients and Methods: A descriptive study of 12 months’ duration was conducted in department of ophthalmology, Federal Government Services Hospital Islamabad. A non-probability convenient sample of 100 patients aged 58 to 77 years was divided equally into two groups, A and B. Each group was again divided into A-1, A2 depending on overall lens diameter of 12 mm, 13 mm respectively and B-1, B-2 for optic diameter of 5.25 mm, 6mm respectively. Each subgroup comprised of 25 patients. Planned phacoemulsification was performed on all patients. Follow up with patient’s symptoms, Snellen’s charts and slit lamp examination was done on day 7, 30 days, 6 months and a year after surgery. All the results were entered on patient's Performa.
Results: In group A where overall IOL size was used, comprising A1(12 mm) & A2(13 mm), 12% (n=3) of (A1) group developed PCO in 1st 12 months and 16% (n=4) of (A2) group developed PCO in 1st 12 months. In group B where optic size was used, comprising B1 (5.25 mm) & B2 (6mm), 24% (6 patients) of B1 group developed PCO and 16% (4 patients) of B-2 group developed PCO during 1st 12 months.
Conclusion: IOL of smaller optic size was associated with higher percentage of early changes of PCO than that of larger optic size. IOL of larger overall size was associated with higher percentage of early changes of PCO than that of smaller overall size. Keywords