Arthralgia an indicator of Vitamin D3 Deficiency and Insufficiency

Abstract

Objective: To determine the prevalence of Vitamin-D deficiency and insufficiency in patients complaining of arthralgia.
Patients and Methods: This cross-sectional study included a group of 332 individuals complaining of arthralgia, selected by consecutive sampling technique. Vitamin-D blood level was performed by ELISA method. Data were entered and analyzed using SPSS Software (Version 15). Mean and Standard deviation was calculated for Quantitative variables and frequency with percentage was presented for Qualitative variables. Chi-Square test was applied to assess any association between Qualitative variables. P value less than 0.05 was considered significant.
Results: Out of 332 individuals who had arthralgia, 9.03% (30).12% (17) and 85.84% (285) had Vitamin-D sufficiency, insufficiency and deficiency. Among total sample population, 75.0% (249) were females and 25.0% (83) were males. In females 8.83% (22), 6.02% (15) and 85.1% (212) had Vitamin-D sufficiency, insufficiency and deficiency (p-value 0.430). Out of 212 Vitamin-D deficient females,48.5% (103), 16.98% (36) and 34.4% (73) had severe, moderate and mild Vitamin-D deficiency(p-value=0.844). In male patients 9.63% (8),2.40% (2) and 87.95% (73) of males had Vitamin-D sufficiency, insufficiency and deficiency (p-value=0.430). Out of 73 Vitamin-D deficient males, 45.20%(33) ,16.43% (12) and 38.3% (28) had severe moderate and mild Vitamin-D deficiency(p-value=0.844). In females Vitamin-D deficiency was found to be most prevalent in age groups of 41-60 years. Whereas in males Vitamin-D deficiency was found to be most prevalent in age groups of 31-40years.
Conclusion: Vitamin D deficiency/insufficiency is an important factor leading to arthralgia, keeping the prevalence rate of about 90% in mind.