Fabrication and Evaluation of Anti-Microbial Efficacy of Root Canal Sealer Using Moringa Oleifera Extract

  • Bakhtawar Yaqoob Rawal Institute of Health Sciences
  • Faisal Moeen Islamic International Dental Hospital, Islamabad
  • Maria Khalid Health Services Academy, Islamabad
  • Sadaf Humayoun Rawal Institute of Health Sciences, Rawalpindi, Pakistan
  • Nousheen Ashraf HITECH Dental College, Taxila
  • Qurat ul Ain Islamic International Dental Hospital, Islamabad
Keywords: Endodontics,Moringa Oleifera, Root canal sealer, Antimicrobial efficacy.

Abstract

of different root canal sealers, new alternative agents are required. These new root canal sealers should ideally be easy to formulate as well as cost-efficient as well. In developing countries, healthcare products derived from natural/herbal sources are of common use. Moringa oleifera is a plant with reported antimicrobial properties. The extract of this plant can be easily formulated, within an economical range. Our study investigated the use of Moringa oleifera extract as a root canal sealer material by fabricating it and assessing its antimicrobial activity.

Objective: To fabricate a root canal sealer by using extract of Moringa Oleifera, evaluate and compare the antimicrobial activity with Endomethasone N.

Methodology: A  new Moringa Oleifera extract (ME) mixture was made and characterization was done using SEM, FT-IR and UV-vis spectrophotometry. In order to evaluate antimicrobial activity, agar well diffusion method was used. The antimicrobial activity was measured by their zone of inhibition against Staphylococcus aureus (ATCC 6538) and Escherichia coli.

Results: The ME mixture exhibited a non-homogenous mixture with a range of particle size distribution. Further, it showed highest zone of inhibition (36.36 + 3.74 mm) against S.aureus in comparison to Endomethasone N.

Conclusion: The results of ME mixture were better than Endomethasone N in terms antimicrobial efficacy. It can be concluded that ME mixture would serve as a better replacement in place of other root canal sealers.

Published
2025-01-07
Section
Original Articles