Cerebral Diffusion Restriction Beyond Neoplasia: Radiological Patterns, Pitfalls, and Pearls. A Pictorial Review

Authors

  • Aroosa Kanwal Department of Radiology, Shifa International Hospital, Islamabad
  • Khurram Khaliq Bhinder Department of Radiology, Shifa International Hospital, Islamabad
  • Madiha Saeed Wahla Department of Radiology, Shifa International Hospital, Islamabad
  • Abeer Shahid Department of Radiology, Shifa International Hospital, Islamabad
  • Amna Mehboob Department of Radiology, Shifa International Hospital, Islamabad
  • Ranam Akhtar Department of Radiology, Shifa International Hospital, Islamabad
  • Amaima Gulzar Department of Radiology, Shifa International Hospital, Islamabad

DOI:

https://doi.org/10.35787/jimdc.v14i3.1396

Abstract

Objective: To highlight various non-proliferative causes and associated diffusion restriction patterns.
Methodology: A collection of cases has been assembled depicting diffusion restriction on MR Brain imaging stemming from non-neoplastic intracranial pathologies.
Results: Various causes were encountered including vascular (infarcts), infectious (abscess, empyema, viral infections), traumatic (hematoma), metabolic (inborn error of metabolism), toxic (carbon-monoxide toxicity) and demyelinating (tumefactive demyelinating disease).
Conclusion: This detailed pictorial helps the radiologist in narrowing the differentials improving diagnostic precision.
Keywords: Cerebral, MRI, Non-neoplastic, Restricted Diffusion.

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Published

26-09-2025

Issue

Vol. 14 No. 3 (2025): July-September

Section

Review Articles

License

Copyright (c) 2025 Journal of Islamabad Medical & Dental College

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Creative Commons License
This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.