Testicular Germ Cell Tumor with a Rare Combination of Seminomatous and Nonseminomatous Components

Abstract

Testicular neoplasms constitute 1% of all tumors in men. With new therapeutic regimens, the cure rate in testicular germ cell tumors is more than 90%. Accurate histologic typing of the neoplasm plays a pivotal role in planning treatment in each case. Most testicular germ cell tumors (GCT) are of mixed type. Various combinations can be present but the occurrence of seminomatous component in mixed germ cell tumor is unusual. We report a case of a 26 years old man who presented with painless enlargement of testis. Histological examination revealed a mixed GCT of seminoma with syncytiotrophoblast cells, immature teratoma and embryonal carcinoma.