Acute Appendicitis: Relationship of Total Leucocyte Count with Per-Operative Stage

Abstract

Objective: To correlate total leucocyte count(TLC) with per-operative stage of acute appendicitis.
Patients and Methods: This cross sectional study was conducted in department of surgery, Pakistan Institute of Medical Sciences (PIMS) from June 2016 to June 2017. A total 77 patients were included through consecutive sampling technique. Statistical Package for Social Sciences (SPSS) version 20 was used to analyze data.
Results: A total of 77 patients were included in the study, among them 47 (61%) were males, and 30(39%) were females. Mean age was 22.25 ± 5.19 years. Mean TLC was 12,900 ± 4087 cells/µL Patients having acute appendicitis were labeled as, acute appendicitis stage I which included 59 (76.6%) patients, Gangrenous appendicitis was named as stage II which included 11 (14.3%) patients. Perforated appendicitis was labeled as Stage III in which 7 (9.1%) patients were inducted. In stage I, mean age was 21.89 ± 5.50 years and mean TLC was 12,344 ± 4162 cells/µl. In stage II, mean age was 22.36 ± 3.90 years and mean of total leukocyte count was 15,072 ± 3497 cells/µl. In stage III, mean age was 25.57 ± 3.50 years and mean leukocyte count was 14,214 ± 4141cells/µl (p-value >0.05).
Conclusion: Significant statistical association was not found in patients in different stages of appendicitis with respect to TLC (p value >0.05), although patients in all stages had raised mean TLC with mean TLC highest in patients having stage II (Gangrenous appendicitis).